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general_organic_solvent_sop [2021/02/26 18:09] – furstgeneral_organic_solvent_sop [2023/01/18 18:59] (current) – bdincau
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 Type of SOP:  0 Process 0 Hazardous Chemical 1 Hazard Class Type of SOP:  0 Process 0 Hazardous Chemical 1 Hazard Class
  
-**HAZARD OVERVIEW**+**1. HAZARD OVERVIEW**
 Flammable and combustible organic solvents are amongst the most dangerous chemicals in the lab.   A measure of how ignitable a particular solvent is the flashpoint ; defined as the lowest temperature at which a material can form an ignitable mixture with air and produce a flame when a source of ignition is present.   The lower the flashpoint, the more easily the liquid can be ignited.   Most common organic solvents in the lab are readily ignited, with the exception of chlorinated solvents like dichloromethane which require more extreme conditions to burn. Flammable and combustible organic solvents are amongst the most dangerous chemicals in the lab.   A measure of how ignitable a particular solvent is the flashpoint ; defined as the lowest temperature at which a material can form an ignitable mixture with air and produce a flame when a source of ignition is present.   The lower the flashpoint, the more easily the liquid can be ignited.   Most common organic solvents in the lab are readily ignited, with the exception of chlorinated solvents like dichloromethane which require more extreme conditions to burn.
 +
 +The international symbol (Globally Harmonized System) for a flammable liquids/gases/solids is:  {{flammable.png|}}
  
 Flammable liquids (flash point < 100oF) are divided into three classes: Flammable liquids (flash point < 100oF) are divided into three classes:
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 {| style="" {| style=""
 |+ Flammable Liquid Classes |+ Flammable Liquid Classes
-!+|
 Class Class
-!+|
 Flash Point Flash Point
-!+|
 Boiling Point Boiling Point
-!+|
 Example Example
 |- |-
 | |
-A2+IA 
 +| 
 +Below 73°F 
 +| 
 +Below 100 °F 
 +| 
 +Ethyl Ether 
 +|- 
 +| 
 +IB 
 +| 
 +Below 73°F 
 +| 
 +At or above 100 °F 
 +| 
 +Acetone, Benzene, Toluene 
 +|- 
 +| 
 +IC 
 +| 
 +At or above 73°F 
 +| 
 +Below 100°F
 | |
-B2+Isopropanol, Xylene
 |} |}
-Class Flash Point Boiling Point Examples 
- 
-IA Below 73°F Below 100 °F Ethyl Ether 
-IB Below 73 °F At or above 100 °F Acetone, Benzene, Toluene 
-IC At or above 73°F and Isopropanol, Xylene 
-below 100°F 
  
 Combustible liquids (flash point > 100oF) are divided into three classes: Combustible liquids (flash point > 100oF) are divided into three classes:
  
-Class Flash Point Examples +{| style="" 
- +|+ Combustible liquids (flash point > 100oF) 
-II  +| 
-100-139 °F +Class 
 +| 
 +Flash Point 
 +| 
 +Example 
 +|- 
 +| 
 +II 
 +| 
 +100-139 °F 
 +|
 Acetic acid, cyclohexane, and mineral spirits Acetic acid, cyclohexane, and mineral spirits
- +|- 
-IIIA  +| 
-140-199 °F +IIIA 
 +| 
 +140-199 °F 
 +|
 Cyclohexanol, formic acid and nitrobenzene Cyclohexanol, formic acid and nitrobenzene
- +|- 
-IIIB +| 
 +IIIB 
 +|
 200 °F or above  200 °F or above
 +|
 Formalin and vegetable oil Formalin and vegetable oil
- +|}
- +
- +
- +
- +
- +
- +
- +
- +
- +
- +
- +
- +
- +
- +
  
  
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 A particular organic solvent may have other hazards beyond their flammability.   For example, benzene is recognized carcinogen.  Check the Safety Data Sheet for the particular solvents in use. A particular organic solvent may have other hazards beyond their flammability.   For example, benzene is recognized carcinogen.  Check the Safety Data Sheet for the particular solvents in use.
  
-The international symbol (Globally Harmonized System) for a flammable liquids/gases/solids is:    
  
-  
-  Diethyl ether initiated fire 
  
-2. PERSONAL PROTECTIVE EQUIPMENT (PPE)+ 
 +** 2. PERSONAL PROTECTIVE EQUIPMENT (PPE) **
 For routine solvent cleaning using IPA, Methanol, Ethanol or Acetone latex gloves are recommended. Nitrile gloves are acceptable for light cleaning of samples where solvent contact is trivial. For routine solvent cleaning using IPA, Methanol, Ethanol or Acetone latex gloves are recommended. Nitrile gloves are acceptable for light cleaning of samples where solvent contact is trivial.
  
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 In general, workers who use flammable liquids will be issued a free fire-resistant Nomex lab coat via the LHAT process. In general, workers who use flammable liquids will be issued a free fire-resistant Nomex lab coat via the LHAT process.
  
-3. ENGINEERING/VENTILATION CONTROLS+**3. ENGINEERING/VENTILATION CONTROLS**
 All chemicals should be transferred and used in an annually certified laboratory chemical fume hood with the sash at the certified position or lower.  The hood flow indicator should be checked to be operating correctly prior to using the hood. For further information see the following pages in Sec. II of the UCSB Chemical Hygiene Plan:   All chemicals should be transferred and used in an annually certified laboratory chemical fume hood with the sash at the certified position or lower.  The hood flow indicator should be checked to be operating correctly prior to using the hood. For further information see the following pages in Sec. II of the UCSB Chemical Hygiene Plan:  
 • Fume Hood Usage Guide  • Fume Hood Usage Guide 
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 • Special Ventilation:  Manipulation of flammable liquids outside of a fume hood may require special ventilation controls in order to minimize exposure and reduce the fire risk. Fume hoods provide the best protection against exposure to flammable liquids in the laboratory and are the preferred ventilation control device.  If your research does not permit the handing of large quantities of flammable liquids in your fume hood, contact EH&S to review the adequacy of all special ventilation. • Special Ventilation:  Manipulation of flammable liquids outside of a fume hood may require special ventilation controls in order to minimize exposure and reduce the fire risk. Fume hoods provide the best protection against exposure to flammable liquids in the laboratory and are the preferred ventilation control device.  If your research does not permit the handing of large quantities of flammable liquids in your fume hood, contact EH&S to review the adequacy of all special ventilation.
  
-4. SPECIAL HANDLING PROCEDURES AND STORAGE REQUIREMENTS+**4. SPECIAL HANDLING PROCEDURES AND STORAGE REQUIREMENTS**
 Use in an area that is properly equipped with a certified eye wash and safety shower that is available within ten seconds of travel. Use in an area that is properly equipped with a certified eye wash and safety shower that is available within ten seconds of travel.
 Store in a tightly closed, labeled container and in a cool, dry, well-ventilated area.  Segregate from incompatible materials.  Repackaged chemicals must be labeled clearly.  For example, squirt bottles and acid/base cleaning baths. Follow any substance-specific storage guidance provided in Safety Data Sheet documentation.   Store in a tightly closed, labeled container and in a cool, dry, well-ventilated area.  Segregate from incompatible materials.  Repackaged chemicals must be labeled clearly.  For example, squirt bottles and acid/base cleaning baths. Follow any substance-specific storage guidance provided in Safety Data Sheet documentation.  
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-5. SPILL AND INCIDENT PROCEDURES+**5. SPILL AND INCIDENT PROCEDURES**
 See directions under the “Chemical Incident” and “Medical Emergency” tabs of the UCSB Emergency Information Flipchart – should already be posted in all labs. See directions under the “Chemical Incident” and “Medical Emergency” tabs of the UCSB Emergency Information Flipchart – should already be posted in all labs.
    
 For those that routinely use flammable liquids, it is strongly recommended that they attend the live version of the EH&S Fundamentals of Laboratory Safety class, where hands-on fire extinguisher training is conducted.   All campus labs should have a fire extinguisher already on-site, generally near the exit door. For those that routinely use flammable liquids, it is strongly recommended that they attend the live version of the EH&S Fundamentals of Laboratory Safety class, where hands-on fire extinguisher training is conducted.   All campus labs should have a fire extinguisher already on-site, generally near the exit door.
  
-6. DECONTAMINATION+**6. DECONTAMINATION**
 Wear proper PPE, decontaminate equipment and bench tops using [soap and water].  Dispose of all used contaminated disposables as hazardous waste per below. Wear proper PPE, decontaminate equipment and bench tops using [soap and water].  Dispose of all used contaminated disposables as hazardous waste per below.
  
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 No prior approval is required for solvent cleaning of samples or lab test fixtures. No prior approval is required for solvent cleaning of samples or lab test fixtures.
  
-9. DESIGNATED AREA +**9. DESIGNATED AREA**
 When possible solvent-related work should be carried out in the fume hood given the volatility and flammability of most solvents. When this is not possible, cleaning test fixtures or samples on the optical tables, for example, make sure that there are no ignition sources nearby. When possible solvent-related work should be carried out in the fume hood given the volatility and flammability of most solvents. When this is not possible, cleaning test fixtures or samples on the optical tables, for example, make sure that there are no ignition sources nearby.
  
-10. SAFETY DATA SHEETS and OTHER REFERENCES+**10. SAFETY DATA SHEETS and OTHER REFERENCES**
 Online SDS can be found at: http://ehs.ucsb.edu/labsafety/msds Online SDS can be found at: http://ehs.ucsb.edu/labsafety/msds
 Prudent Practices in the Laboratory, 2011, see Secs. 4.D and 6.F for flammable liquids http://www.nap.edu/openbook.php?record_id=12654&page=R15 Prudent Practices in the Laboratory, 2011, see Secs. 4.D and 6.F for flammable liquids http://www.nap.edu/openbook.php?record_id=12654&page=R15
  
  
-11. LAB-SPECIFIC INFORMATION (required)  (Examples of appropriate content)+**11. LAB-SPECIFIC INFORMATION (required)**  (Examples of appropriate content)
 In general solvents are used for simple cleaning of samples and tooling. Squirt bottles of solvents are stored in the white bin in the fume hood. These bottles can be refilled from the large bottles stored under the fume hood. In general solvents are used for simple cleaning of samples and tooling. Squirt bottles of solvents are stored in the white bin in the fume hood. These bottles can be refilled from the large bottles stored under the fume hood.
  
general_organic_solvent_sop.1614362971.txt.gz · Last modified: 2021/02/26 18:09 by furst